[SARS vaccines].
Identifieur interne : 002F63 ( Main/Exploration ); précédent : 002F62; suivant : 002F64[SARS vaccines].
Auteurs : Fumihiro TaguchiSource :
- Nihon rinsho. Japanese journal of clinical medicine [ 0047-1852 ] ; 2008.
Descripteurs français
- KwdFr :
- MESH :
- effets indésirables : Vaccins antiviraux.
- immunologie : Virus du SRAS.
- virologie : Syndrome respiratoire aigu sévère.
- Animaux, Conception de médicament, Humains, Protéines virales, Syndrome respiratoire aigu sévère, Vaccins atténués, Vaccins sous-unitaires, Vaccins à ADN, Vecteurs génétiques.
English descriptors
- KwdEn :
- MESH :
- chemical , adverse effects : Viral Vaccines.
- chemical : Vaccines, Attenuated, Vaccines, DNA, Vaccines, Subunit, Viral Proteins.
- immunology : SARS Virus.
- prevention & control : Severe Acute Respiratory Syndrome.
- virology : Severe Acute Respiratory Syndrome.
- Animals, Drug Design, Genetic Vectors, Humans.
Abstract
Severe acute respiratory syndrome (SARS) is an emerging disease derived from wild animals and is highly pathogenic with a high mortality. A novel coronavirus SARS coronavirus was identified to be a causative agent for SARS. Since its discovery, many trials have been executed to establish the prophylactic and therapeutics toward SARS using laboratory animals. A number of different types of vaccines, such as inactivated virus vaccine, subunit vaccine, DNA vaccine and vaccine using viral expression vector as well as attenuated live vaccine so far reported indicate that neutralizing antibodies play an important role for protection. However, vaccine applicable to humans with the high efficacy and safety has not yet been reported.
PubMed: 18939499
Affiliations:
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Le document en format XML
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Japanese journal of clinical medicine</title><idno type="ISSN">0047-1852</idno><imprint><date when="2008" type="published">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Drug Design</term><term>Genetic Vectors</term><term>Humans</term><term>SARS Virus (immunology)</term><term>Severe Acute Respiratory Syndrome (prevention & control)</term><term>Severe Acute Respiratory Syndrome (virology)</term><term>Vaccines, Attenuated</term><term>Vaccines, DNA</term><term>Vaccines, Subunit</term><term>Viral Proteins</term><term>Viral Vaccines (adverse effects)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Conception de médicament</term><term>Humains</term><term>Protéines virales</term><term>Syndrome respiratoire aigu sévère ()</term><term>Syndrome respiratoire aigu sévère (virologie)</term><term>Vaccins antiviraux (effets indésirables)</term><term>Vaccins atténués</term><term>Vaccins sous-unitaires</term><term>Vaccins à ADN</term><term>Vecteurs génétiques</term><term>Virus du SRAS (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Viral Vaccines</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Vaccines, Attenuated</term><term>Vaccines, DNA</term><term>Vaccines, Subunit</term><term>Viral Proteins</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Vaccins antiviraux</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Drug Design</term><term>Genetic Vectors</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Conception de médicament</term><term>Humains</term><term>Protéines virales</term><term>Syndrome respiratoire aigu sévère</term><term>Vaccins atténués</term><term>Vaccins sous-unitaires</term><term>Vaccins à ADN</term><term>Vecteurs génétiques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Severe acute respiratory syndrome (SARS) is an emerging disease derived from wild animals and is highly pathogenic with a high mortality. A novel coronavirus SARS coronavirus was identified to be a causative agent for SARS. Since its discovery, many trials have been executed to establish the prophylactic and therapeutics toward SARS using laboratory animals. A number of different types of vaccines, such as inactivated virus vaccine, subunit vaccine, DNA vaccine and vaccine using viral expression vector as well as attenuated live vaccine so far reported indicate that neutralizing antibodies play an important role for protection. However, vaccine applicable to humans with the high efficacy and safety has not yet been reported.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Taguchi, Fumihiro" sort="Taguchi, Fumihiro" uniqKey="Taguchi F" first="Fumihiro" last="Taguchi">Fumihiro Taguchi</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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